Cybernetic Cells
September 5th, 2006 by
Mike Gene

Concepts from engineering continue to produce much fruit in biological research.
From Here -
This feedback loop acts as a sensor that ensures there are sufficient primordial germ cells in the ovary at the end of larval development. The level of EGF signaling is used to keep the amount of germ cells just right, so that there are not too few and not too many of them.
The scientists had a hunch that PGCs and the somatic cells communicate. “Dr. Gilboa’s experiments clearly show there is a feedback mechanism, whereby the PGCs send a signal to the somatic cells to keep them alive and the somatic cells send a signal back to the germ cells, keeping them in check,” says Dr. Lehmann.
Feedback mechanisms and communcation theory are teleological concepts that were imported into biology decades ago. As you can see, these design concepts are now deeply entrenched in the heart of biological research. The reason is simple. If you are to describe advanced technology, you will need technological concepts.
Also, the hypothesis of superficial diversity, something that we’d predict if evolution was front-loaded, continues to make predictions:
Genetics research is revealing commonalities across species; the fruit fly delivers cues. It is an animal in which processes are first discovered and which are later confirmed in humans. “Evolution works–what works for the fruit fly is the same principle that nature has put in place for us,” says Dr. Gilboa.
Ah yes, the design of evolution. So unpredictably predictable.
Posted in General |

December 22nd, 2006 at 7:57 am
[…] Homeostasis is the essence of life. A molecular example is iron homeostasis, where a large protein, IRP1, not only has dual functions, but can serve as both sensor and effector in controlling iron concentration levels in the cell. A recent study shows that its ability to control gene expression is surprisingly sophisticated. IRP1 is a very large protein, composed of about 900 amino acids arranged into four major domains. […]